Cycloastragenol

Cycloastragenol has a similar chemical structure to that of the Astragaloside IV molecule, but it is smaller and significantly more bioavailable, enabling lower doses to be taken. It is already used as an immunostimulant because of its ability to increase T lymphocyte proliferation. However, it is its exceptional anti-aging properties that are of increasing interest to the scientific community. Cycloastragenol stimulates the repair of DNA damage by activating telomerase, a nucleoprotein enzyme that catalyzes the synthesis and growth of telomeric DNA. Telomeres are made of thin filaments and are found at the tips of chromosomes. Maintaining their stability enables cells to avoid replicative senescence and indefinite proliferation beyond the ‘Hayflick limit. Telomeres shorten with each cycle of cell division, or when subjected to oxidative stress. Until now, this has been an unavoidable mechanism of aging.